So What Is POEMS Syndrome?

This is my understanding by reading various articles. It is not a medically, authoritative article, but is simply how I understand what I have.

Must be present:

- Polyneuropathy

- Monoclonal plasma cell disorder (myeloma)

Strong indicators:

- Sclerotic bone lesions

- Elevated VEGF. Signal protein to create muscle after exercise/new blood vessels.

- Castleman's Disease (non-cancerous tumors in lymph nodes)

- Elevated paraprotein (m-protein)

Possible indicators:

- Endocrinopathy (gynecomastia/ hypothyroid)

- Organomegaly (spenomegaly)

- Papilloedema

-Weight loss > 10 lbs

- Significant fatigue

- Erectile dysfunction